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FGI-104

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FGI-104 is an experimental broad-spectrum antiviral drug. It works by blocking TSG101, a human protein that helps transport new virus particles out of infected cells, which disrupts the virus replication cycle.

The drug has shown activity against a range of viruses in studies, including hepatitis B, hepatitis C, HIV, Ebola virus, and Venezuelan equine encephalitis virus.

In preclinical tests, FGI-104 protected mice from Ebola virus disease, providing early evidence of potential antiviral effects in animals.

FGI-104 is not yet approved for use and is classified in the United States as an Investigational New Drug, indicating it is being studied in early development.


This page was last edited on 2 February 2026, at 10:52 (CET).