MPMI (drug)

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MPMI, or 3-(N-methylpyrrolidin-3-ylmethyl)indole (also called N-methyl-α,N-trimethylenetryptamine), is a chemical that acts as a serotonin receptor agonist. It is a pyrrolidinylmethylindole and a cyclized tryptamine. It has been studied mainly as an analogue and trace impurity of the migraine drug eletriptan; beyond this, it is not widely known.

Analogues and related compounds include 4-HO-MPMI, 5-MeO-MPMI, 5F-MPMI, eletriptan, CP-122288, CP-135807, 10,11-secoergoline (α,N-Pip-T), pyr-T, SN-22, and α,N,N-trimethyltryptamine.

In terms of legal status, MPMI is not a controlled substance in Canada as of 2025, and it is not explicitly controlled in the United States. However, it could fall under the Federal Analogue Act if it is intended for human consumption.