Aquaretic

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An aquaretic is a type of drug that helps the body remove water in urine without losing electrolytes like salt. They aren’t true diuretics, though they’re sometimes called that. Aquaretics increase urine output while keeping sodium and chloride levels steady, which can be helpful in treating hyponatremia. Some herbal medicines, such as horsetail and nettle leaves, are also considered aquaretics. Synthetic aquaretics work by blocking vasopressin receptors and include conivaptan, tolvaptan, demeclocycline, mozavaptan (OPC-31260), and lithium. Conivaptan and tolvaptan are approved in the United States for treating SIADH, while mozavaptan is approved in Japan.