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MAM-2201

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MAM-2201 is a synthetic cannabinoid found in some illegal cannabis-like products. It acts like THC by activating brain receptors, especially CB1 and CB2, and has been shown in studies to influence brain function in animals.

What it is and where it comes from
- MAM-2201 is a hybrid of two other synthetic cannabinoids, JWH-122 and AM-2201.
- It was first identified in Europe (the Netherlands and Germany) in June 2011 in synthetic cannabis products.
- It has also been called 4'-methyl-AM-2201 and 5"-fluoro-JWH-122.

How it behaves in the body
- Research indicates MAM-2201 binds to and activates CB1 and CB2 receptors.
- In animal tests, it could substitute for THC, and studies have shown possible neurofunctional disruptions.

Legal status around the world
- United States: Schedule I substance (illegal).
- United Kingdom: Class B illegal drug.
- Canada: Schedule II.
- Germany: Anlage II (not prescribable, only for approved uses).
- New Zealand: Temporary class drug since July 13, 2012.
- China: Controlled substance as of 2015.
- Brazil: Prohibited (Class F2) under psychotropic controls.

Quick facts
- Chemical formula: C25H24FNOM
- Molar mass: 373.471 g/mol
- IUPAC name: (1-(5-Fluoropentyl)-1H-indol-3-yl)(4-methyl-1-naphthalenyl)methanone
- Other identifiers include CAS number 1354631-24-5 and various database IDs.


This page was last edited on 2 February 2026, at 04:42 (CET).