S-(2-Aminoethyl)isothiuronium bromide hydrobromide
S-(2-Aminoethyl)isothiuronium bromide hydrobromide, or AET, is a dihydrobromide salt of an isothiouronium compound used mainly as a reducing agent in chemistry. It does not have a free thiol group like some other reducing agents, but in water it slowly forms temporary thiol-containing intermediates that can reduce disulfide bonds.
One common use is in hematology research, where treating red blood cells with AET creates PNH-like (paroxysmal nocturnal hemoglobinuria–like) cells, a laboratory model for study.
Other names include beta-Aminoethylisothiourea and the IUPAC name 2-aminoethyl carbamimidothioate; dihydrobromide. The formula is C3H11Br2N3S with a molar mass of about 281.0 g/mol.
Safety: AET is hazardous and should be handled with appropriate laboratory safety precautions to avoid ingestion, inhalation, or skin/eye contact.
This page was last edited on 3 February 2026, at 04:35 (CET).