Periglomerular cell

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Periglomerular cells are inhibitory neurons in the olfactory bulb. They work with granule cells to provide lateral inhibition, helping to sharpen odor signals. They form inhibitory synapses onto the main relay neurons, mitral and tufted cells, using GABA to reduce their activity and improve contrast in odor representations. These cells are part of the local glomerular circuit that refines how smells are processed.