Membrane Protein Structural Dynamics Consortium
Membrane Protein Structural Dynamics Consortium (MPSDC) is a large, interdisciplinary collaboration formed in May 2010 at the University of Chicago. Led by Eduardo Perozo, Ph.D., its goal is to understand how the structure and movement of membrane proteins relate to their functions, focusing on energy-related signaling (ion channels and receptors) and energy interconversion (transporters and pumps). Funded by a five-year Glue Grant from the National Institute of General Medical Sciences (NIGMS), the project received $22.5 million (grant GM087519).
The consortium is organized into three Scientific Cores and seven Bridging Projects that share resources and develop new methods. Scientific Cores support research in membrane protein expression and production, synthetic antigen binder generation, and innovative computational approaches to interpret experimental data. Bridging Projects connect investigators and expand the work in new directions, enhancing the overall effort.
MPSDC was created to pursue high-resolution approaches to membrane protein structure and dynamics, addressing a critical need in the field. The grant's renewal would depend on project success and assessment, potentially in 2015. Website: www.memprotein.org
This page was last edited on 3 February 2026, at 18:35 (CET).