Chloridazon-catechol dioxygenase

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Chloridazon-catechol dioxygenase (EC 1.13.11.36) is an iron-dependent enzyme that helps break down the herbicide chloridazon. It belongs to the oxidoreductases and acts as an oxygenase, using oxygen to modify its substrate and open its ring. In the reaction, the substrate 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone and molecular oxygen are converted into 5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone. Systematic name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing). The enzyme uses iron as a cofactor.