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Succinaldehyde

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Succinaldehyde, also known as butanedial, is an organic chemical with the formula C4H6O2. It is a colorless, viscous liquid.

Key points:
- In water it forms a cyclic hydrate; in methanol it forms a cyclic acetal called 2,5-dimethoxytetrahydrofuran.
- It can crosslink proteins, but it is used less often than glutaraldehyde.
- It is a precursor to tropinone (a compound used in making tropane alkaloids).

How it’s made:
- Oxidation of tetrahydrofuran with chlorine, followed by hydrolysis.
- Hydroformylation of acrolein (or its acetals).
- Oxidation of 2,5-dimethoxytetrahydrofuran with hydrogen peroxide.

Properties:
- Molar mass: 86.09 g/mol
- Density: 1.064 g/cm3
- Boiling point: about 58 °C at 9 mmHg
- Standard state data are given at 25 °C and 100 kPa

Formula: C4H6O2


This page was last edited on 2 February 2026, at 19:40 (CET).