SR1 RNA

Content sourced from Wikipedia, licensed under CC BY-SA 3.0.

SR1 RNA is a small RNA molecule found in Bacillus bacteria and related species. It has two jobs at once. First, as a regulator, it pairs with the ahrC/argR mRNA to prevent its translation. AhrC acts as the arginine repressor: it normally lowers the production of enzymes that make arginine and increases the enzymes that break it down, by controlling rocABC and rocDEF operons. By blocking ahrC, SR1 influences how arginine is processed in the cell. Second, SR1 encodes a tiny protein called SR1P. SR1P binds to the enzyme GapA and helps stabilize GapA mRNA, supporting its production. The amount of SR1 RNA in the cell is controlled by the regulatory proteins CcpA and CcpN.