2010 Liga de Fútbol Profesional Boliviano

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The 2010 season of Bolivia’s top-flight football, Liga de Fútbol Profesional Boliviano, was the 34th edition. It featured two championships, Apertura and Clausura, plus a mid-season Torneo de Invierno (Winter Tournament). Nacional Potosí was relegated from the previous season and replaced by Guabirá.

Apertura
- Champion: Jorge Wilstermann (their 5th Apertura title)
- Top scorer: Cristian Díaz – 18 goals
- Relegation: Jorge Wilstermann finished last and were relegated
- Notable results: Bolivar 6-1 Real Mamoré; Universitario 5-0 Real Potosí (biggest home wins); San José 0-3 Aurora; La Paz 1-4 San José (biggest away wins); Aurora 4-4 San José; Aurora 3-5 The Strongest; Real Potosí 5-3 Bolívar (highest-scoring games)
- Format: The Apertura had two groups, a cross-group rivalry, and two hexagonal phases (Winner’s Hexagonal to decide the champion; Loser’s Hexagonal for other qualifications). The winner earned a 2011 Copa Libertadores spot (Bolivia 2 berth).

Clausura
- Champion: Oriente Petrolero (their 4th Clausura title)
- Format: A double round-robin league over 22 rounds to determine the Clausura champion
- Continental spots: The Clausura determined qualification for the 2011 Copa Libertadores and 2011 Copa Sudamericana (Bolivia 1, Bolivia 3 for Libertadores; Bolivia 2 for Sudamericana)

Continental qualifications
- 2011 Copa Libertadores: Jorge Wilstermann, Oriente Petrolero, Bolívar
- 2010 Copa Sudamericana: Universitario
- 2011 Copa Sudamericana: Aurora, The Strongest, San José

Torneo de Invierno (Winter Tournament)
- A mid-season knockout competition; the winner earned a berth to the 2011 Copa Sudamericana (Bolivia 3 berth)

Promotions and relegations
- Relegation is decided after the Clausura based on a two-year average; the bottom team is relegated to the Bolivian regional leagues, and the next-worst enters a playoff with the runner-up of the 2010 Copa Simón Bolívar
- 2009 relegated team: Nacional Potosí; replaced by Guabirá (Copa Simón Bolívar champion)

Season timeline
- Apertura began February 20 and ended June 9, just before the 2010 FIFA World Cup
- The Apertura second phase began May 8
- Torneo de Invierno ran mid-season, alongside the World Cup period

Notes
- Oriente Petrolero’s Clausura success helped them secure 2011 Libertadores qualification, which affected subsequent Sudamericana slots (San José earned a 2011 Sudamericana spot as a result)