Alazopeptin
Alazopeptin is an antibiotic with moderate activity against Trypanosoma parasites and some anti-cancer (antitumor) effects. It was first found in a soil-dwelling bacterium called Streptacidiphilus griseoplanus from soil near Williamsburg, Iowa. It has also been isolated from Kitasatospora azatica, and today it is mainly produced by fermenting these organisms.
Chemically, alazopeptin is a small molecule made up of three amino-acid units (a tripeptide): it contains two units of 6-diazo-5-oxo-L-norleucine and one unit of L-alanine.
In 2021, scientists clarified the biosynthetic pathway—how the producing organism makes alazopeptin. Because of its biological activities, alazopeptin is of interest as a potential cancer-related or immunomodulatory drug, though it remains primarily a research compound.
This page was last edited on 2 February 2026, at 15:16 (CET).